| Rank | Club | Points | GP | W | L | D | G | GC | GD |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
Philadelphia Union
|
40 | 20 | 12 | 4 | 4 | 35 | 20 | 15 |
| 2 |
San Diego
|
39 | 20 | 12 | 5 | 3 | 41 | 25 | 16 |
| 3 |
FC Cincinnati
|
39 | 20 | 12 | 5 | 3 | 31 | 26 | 5 |
| 4 |
Nashville SC
|
38 | 20 | 11 | 4 | 5 | 36 | 23 | 13 |
| 5 |
Vancouver Whitecaps
|
38 | 20 | 11 | 4 | 5 | 35 | 22 | 13 |
| 6 |
Minnesota United FC
|
37 | 21 | 10 | 4 | 7 | 35 | 24 | 11 |
| 7 |
Columbus Crew
|
37 | 20 | 10 | 3 | 7 | 33 | 26 | 7 |
| 8 |
Orlando City SC
|
33 | 20 | 9 | 5 | 6 | 37 | 26 | 11 |
| 9 |
New York City FC
|
31 | 20 | 9 | 7 | 4 | 27 | 22 | 5 |
| 10 |
Portland Timbers
|
30 | 19 | 8 | 5 | 6 | 28 | 27 | 1 |
| 11 |
Inter Miami
|
29 | 16 | 8 | 3 | 5 | 36 | 27 | 9 |
| 12 |
New York Red Bulls
|
29 | 20 | 8 | 7 | 5 | 32 | 24 | 8 |
| 13 |
Seattle Sounders
|
29 | 19 | 8 | 6 | 5 | 27 | 25 | 2 |
| 14 |
Chicago Fire
|
28 | 19 | 8 | 7 | 4 | 38 | 34 | 4 |
| 15 |
San Jose Earthquakes
|
27 | 20 | 7 | 7 | 6 | 40 | 32 | 8 |
| 16 |
Los Angeles FC
|
26 | 17 | 7 | 5 | 5 | 30 | 24 | 6 |
| 17 |
Colorado Rapids
|
26 | 21 | 7 | 9 | 5 | 24 | 30 | -6 |
| 18 |
Austin
|
26 | 20 | 7 | 8 | 5 | 15 | 23 | -8 |
| 19 |
Charlotte
|
25 | 20 | 8 | 11 | 1 | 32 | 34 | -2 |
| 20 |
New England Revolution
|
24 | 18 | 6 | 6 | 6 | 24 | 21 | 3 |
| 21 |
Sporting Kansas City
|
23 | 21 | 6 | 10 | 5 | 33 | 38 | -5 |
| 22 |
Houston Dynamo
|
23 | 20 | 6 | 9 | 5 | 25 | 31 | -6 |
| 23 |
FC Dallas
|
21 | 20 | 5 | 9 | 6 | 27 | 37 | -10 |
| 24 |
Real Salt Lake
|
19 | 19 | 5 | 10 | 4 | 19 | 26 | -7 |
| 25 |
DC United
|
18 | 20 | 4 | 10 | 6 | 17 | 39 | -22 |
| 26 |
Toronto FC
|
17 | 20 | 4 | 11 | 5 | 23 | 28 | -5 |
| 27 |
Atlanta United FC
|
17 | 19 | 4 | 10 | 5 | 22 | 37 | -15 |
| 28 |
St. Louis City
|
15 | 20 | 3 | 11 | 6 | 19 | 31 | -12 |
| 29 |
CF Montreal
|
14 | 20 | 3 | 12 | 5 | 17 | 36 | -19 |
| 30 |
Los Angeles Galaxy
|
12 | 21 | 2 | 13 | 6 | 22 | 42 | -20 |
